Search on: 2-OXO ACID CARBOXY-LYASE 
Descriptors Found: 1
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Descriptor English:   Pyruvate Decarboxylase 
Descriptor Spanish:   Piruvato Descarboxilasa 
Descriptor Portuguese:   Piruvato Descarboxilase 
Synonyms English:   2-Oxo Acid Carboxy-Lyase
alpha-Carboxylase
alpha-Ketoacid Carboxylase
Pyruvic Decarboxylase  
Tree Number:   D08.811.520.224.125.750
Definition English:   Catalyzes the decarboxylation of an alpha keto acid to an aldehyde and carbon dioxide. Thiamine pyrophosphate is an essential cofactor. In lower organisms, which ferment glucose to ethanol and carbon dioxide, the enzyme irreversibly decarboxylates pyruvate to acetaldehyde. EC 4.1.1.1. 
History Note English:   91(75); was see under CARBOXY-LYASES 1975-90 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   22630 
Unique Identifier:   D011767 

Occurrence in VHL:
 

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